The National Centre for Mathematics and Computer Science (CWI) and the  Netherlands Cancer Institute (NKI), both located in Amsterdam, The  Netherlands, invite applications for a jointly advised PhD position on Subnetwork module construction for improved diagnostic classification  and subtyping CWI is the national research institute for mathematics and computer  science in the Netherlands. CWI performs frontier research in  mathematics and computer science and transfers new knowledge in these  fields to society in general and trade and industry in particular. The  newly established Life Sciences group develops algorithms, theory, and  models, and performs simulations for a wide range of biological topics  with a strong focus on systems biology. The Netherlands Cancer Institute is the only dedicated cancer center  in the Netherlands and maintains an important role as a national and  international center of scientific and clinical expertise, development  and training.  Research within the Netherlands Cancer Institute covers  all major areas of cancer research, with a strong emphasis on  translational research. The Bioinformatics and Statistics group  closely collaborates with basic scientists and clinicians and conducts  research on a wide range of topics, focusing on integrative  bioinformatics. The opening is a research position within the field of bioinformatics/ computational biology and will be a joint appointment between the two  institutes. The research will be carried out in close collaboration of  the involved partners. The successful candidate will contribute to building better predictors  of disease outcome based on functional interaction network modules,  which are predictive of a specified phenotype, e.g., outcome in  cancer. To this end, development of new algorithms to detect these  modules given a complex interaction graph has to be combined with protocols for building predictive classifiers given the activation  patterns of the retrieved modules. The ideal candidate has a background in bioinformatics, computer  science, statistics, physics, or biology, strong algorithmic and/or  machine learning skills, and experience with the analysis of high- throughput data. Applications consisting of motivation letter, Curriculum Vitae, a list  of publications, and a list of references should be send by email  before 15 March 2009 to Dr. G.W. Klau or Dr. L.F.A. Wessels, who can  also supply further information about this position. Please see the  website http://www.cwi.nl/en/node/961 for further details.