The Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico is the largest public research hospital in Italy. Being affiliated with the University of Milan, it oversees training of hematology residents and fellows and has a decade-long tradition of successful research on hematology and particularly Multiple Myeloma (MM). Prof. Niccolò Bolli, a long-standing leader in MM genomics with a strong focus on translational research has established a Research Lab focused on: i) the role of mutations and copy number changes in re-shaping the myeloma genome landscape from asymptomatic to symptomatic stages; ii) the transcriptomic landscape plasma cell dyscrasias at single cell level, using single-cell RNAseq (scRNAseq) analysis coupled with BCR sequencing; iii) evaluate microenvironmental changes at the single-cell level within the bone marrow niche; iv) identify and characterize the "cellular reservoir" responsible for therapy resistance and its impact on Minimal Residual Disease (MRD) persistence.

We are seeking a highly motivated and talented individual to fill a fixed-term full-time position, starting in May-June 2025 (with flexibility) as:
Postdoctoral Researcher / Computational Biologist (f/m/d) with a focus on genomics (WGS, TDS) and single cell RNA sequencing data computational biology.

The successful candidate will be part of a dynamic, interdisciplinary team operating at the intersection of computational biology and translational medicine.

This position offers a unique opportunity to contribute to cutting-edge research leveraging state-of-the-art computational infrastructure and genomics/transcriptomics data to address fundamental biological questions in Multiple Myeloma field.

Key Responsibilities:

• Develop and apply computational workflows to analyze large-scale genomics and transcriptomics datasets.
• Collaborate closely with experimental scientists and clinicians
• Contribute to the development of novel methods for data integration and interpretation
• Communicate results effectively through presentations, progress-reports and peer-reviewedpublications.

Qualifications:

• Master’s degree/ PhD in bioinformatics, computational biology, data science, biology or related fields
• Expertise in data analysis, data visualization, and/or high-throughput genomics or transcriptomics
• Strong computer programming skills are required (i.e. R, Python, Bash and machine learning)
• Experience with statistics is a strong advantage.
• Communication skills, both written and oral, and the ability to work collaboratively in an interdisciplinary environment.
• Good level of English

What We Offer

• A stimulating and supportive environment
• Access to computational resources.
• Opportunities for professional development and training, with international scientific collaborations
• An international research community
• Flexible working hours

Application
Please submit informal application requests via mail, including a cover letter detailing your research interests and expertise, a CV with a publication list, and the contact information for two references.

Mail to all three Lab members: niccolo.bolli@unimi.it; francy.la84@hotmail.it; marta.lionetti@unimi.it.

Start date
May-June 2025, with some flexibility allowed
We look forward to receiving your application, even if you do not fully match the job profile.
Looking forward to welcoming an innovative scientist to our team!