Applications are invited for the PhD studentship “Rational design of selective modulators of skeletal myosin” funded by Muscular Dystrophy UK (MDUK) and starting from January 2020 in Dr. Arianna Fornili’s group at Queen Mary University of London and Dr. Julien Ochala’s group at King's College London.

The aim of the project is to use a combination of molecular modelling and biophysics techniques to design and test small molecules that can selectively target skeletal myosin, a key component of the molecular machinery involved in muscle contraction. The main outcome will be a new set of potential myosin modulators, that is compounds that can bind to myosin and modify its function, to be used as leads in the development of drugs for severe muscle diseases such as nemaline myopathy.

More information can be found at
https://www.findaphd.com/phds/project/rational-design-of-selective-modulators-of-skeletal-myosin/?p105203