One position  is avaliable at  Spedali Civili di Brescia (Brescia, Italy) jointly with the Unit of Biostatistics & Bioinformatics, University of Brescia, for a Bioinformatician/Biostatistician to work in a project on Genetic and immunological study of children with Crohn's disease


Crohn's disease (CD), is a life-long disease, and its incidence is rapidly increasing, in particular in industrialized countries.

About 25% of CD cases have an onset in childhood, and CD cases with childhood-onset are more aggressive and severe than adult-onset CD. Despite numerous attempts to elucidate the pathogenesis of CD, it still remains largely unclear, and despite CD is considered to some extent a disease depending from the environment, there is no known way to prevent it.

Recent evidence suggests that CD may result from abnormal interactions between the environment -through commensal bacteria in the gut- and genetic factors.


The project will:


 1) Investigate the genetic basis of CD in children;

2) Elucidate the role of intestinal microbioma and  mucosal immunity in CD;

3) Understand the effects of thalidomide, an emerging therapy for CD, on hematopoietic and

mucosal immunity in CD.

The desidered profile is has a background in bioinformatics and biostatistics, with experience in NGS data modelling


Salary

The position will be funded for 3-years.



To apply

Please send your application including a synopsis of research interest, Curriculum vitae, and possibly a contact for reference by email to:

Stefano Calza, e-mail: stefano.calza@unibs.it


Skype interviews first and then in person interviews will be arranged for few selected candidates.