Applications for the Bioinformatics Training Course 

WESRDA13  -  Whole Exome Sequencing and RNA-seq data analysis

with Ignacio Medina and Javier Santoyo-Lopez

are now OPEN!

   IMPORTANT DATES for this Course
   Deadline for applications: *September 27th 2013*
   Notification of acceptance within 72 hours of application
(working days count)
   Course date: *October 8th to October 11th 2013*

Details about the course including instructions on how to apply can be
found in the appropriate page of the GTPB website

http://gtpb.igc.gulbenkian.pt/bicourses/WESRDA13/

We hope that you enjoy it.

Course description
High-throughput technologies such as next generation sequencing (NGS)
are characterized for producing massive a mounts of data. These
technologies for example can allow to describe all variants in a
genome or to detect the whole set of transcripts that are present in a
cell or tissue. However, at the same time, posses new challenges in
the way the data has to be analyzed, annotated and interpreted which
are not trivial.

Whole Exome Sequencing produces sequence data using NGS assays and
allows the study of genetic variations in the exonic regions of all
genes that can be transformed in biological information at an
unprecedented level of detail. Traditionally transcriptomic analysis
has been used to find genes that are differentially expressed among
distinct experimental conditions, or correlated to diverse parameters.
Currently, NGS technologies such as RNA-seq can also allow to
digitally quantify all, known and unknown, transcripts or to discover
new isoforms and splice sites for all the genes.

However, NGS data analysis can be a major bottleneck for many
researchers which are still applying inefficient tools for the
processing of the data and inadequate methods for the interpretation
of their results in order to have meaningful results. This course
covers state-of-the-art tools and methods for NGS RNA-seq and exome
variant data analysis, which are of major relevance in today's genomic
and gene expression studies.

The aim of this course is to familiarise course participants with the
latest analysis methodologies and to provide hands-on training on the
analytical approaches implemented for RNA-seq data and whole exome
variant analysis.