We are seeking a motivated and skilled bioinformatician to join the research group of Prof. Enrico Tiacci at the Institute of Hematology and Center for Hemato-Oncology Research in the University and Hospital of Perugia, Italy.
The focus of Prof. Tiacci's group, funded by several research agencies including the European Research Council (ERC), is to clarify by next-generation sequencing the genetic pathogenesis of human lymphomas and leukemias (in particular Hodgkin lymphoma and hairy cell leukemia), and to translate this knowledge in the clinic by developing new precision diagnostic and therapeutic tools (as exemplified by recent publications in top journals, e.g. Tiacci et al., NEJM 2011; Tiacci et al, Blood 2012; Tiacci et al., NEJM 2015; Pettirossi et al., Blood 2015; Tiacci et al., JCO 2017; Tiacci et al., Blood 2018; Tiacci et al, NEJM 2018).
Prof. Tiacci's group is located in the newly built Center for Hemato-Oncology Research, a beautiful building with outstanding design, state-of-the-art laboratories and technology platforms, which is strategically located next to the Institute of Hematology, a major tertiary care academic hematological clinic in central Italy acting as a reference center also for patients from other part of the country and from abroad. The project will be carried out in a stimulating biology and molecular medicine research environment shared with other principal investigators (Prof. Brunangelo Falini and Prof. Maria P. Martelli, also ERC grantees). All equipment needed for state-of-the art genomic investigations, including deep sequencing and adequate computational resources, is available and accessible within the building.
The candidate should be an enthusiastic, creative, proactive, problem-solving person with a strong background in bioinformatics and previous experience with next-generation sequencing (NGS), ideally in cancer genetics. In particular, familiarity with the analysis of whole-exome/whole-genome sequencing data from tumor verus normal paired DNA, as well as of RNA-seq and ChIP-seq data, would be a plus.
The candidate should have a PhD or equivalent research experience in bioinformatics, computational biology or related subjects; should be familiar with common NGS tools (BWA, Samtools, GATK, etc.), with Unix/Linux operating systems and, ideally, with high-performance computing (HPC) clusters; should have good scripting/programming skills (R/Python/Bash); and should have a good command of English.
The candidate should apply by email (enrico.tiacci@unipg.it) with a cover letter describing his/her career goals and explaining why he/she is the ideal candidate for this position, a detailed CV, and 2-3 letters of reference or contact details of 2-3 referees.
Type of contract: Research fellowship (Assegno di ricerca).
The next application deadline is September 30, 2020, but applications will be reviewed on a rolling basis and the call will remain open until the position is filled.
Expected starting date: November 1, 2020.