Program
| Wednesday, 27 May | |
| 12:30 - 14:00 | Registration & sign-in |
| 14:00 - 14:10 | Welcome |
Translational Bioinformatics chair(s) to be defined |
|
| 14:10 - 14:45 | Graziano Pesole University of Bari PREPARATA LECTURE Accurate Genotyping and Tissue-Specific Expression Analysis of the Human Mitochondrial Genome integrating whole genome and direct long-read RNA sequencing data |
| 14:45 | Martina Varisco |Oral Presentation| Beyond the mechanism of action: a data-driven interpretable model reveals new determinants of cancer drug sensitivity |
| 15:00 | Dora Tortarolo |Oral Presentation| Gut microbiome signatures at Multiple Sclerosis onset as an independent early prognostic factor for disease course |
| 15:15 | Fabiana Galluzzo |Oral Presentation| Molecular determinants of antibiotic-ribosome recognition: a comparative analysis |
| 15:30 - 15:40 | Presentation of YOUNG BITS, RSG-Italy, SIB Young, CINI Young-InfoLife groups |
| 15:40 - 16:00 | Coffee break |
| 16:00 - 19:00 | BITS members Assembly |
| 19:30 - 21:00 | AperiBITS |
| Thursday, 28 May | |
Databases, interoperability and research infrastructure chair(s) to be defined |
|
| 09:00 - 09:45 | Paul Thomas University of Southern California & Swiss Institute of Bioinformatics keynote Homology as a tool for predicting gene functions: what are the limitations and can we push past them? |
| 09:45 | Giada Malatesta |Oral Presentation| Bridging Health Research and Innovation: The Strategic Role of ICSC and the IT4LIA AI Factory in Building a Federated, AIReady Ecosystem for Biomedical Data |
| 10:00 | Mehdi Zoubiri |Oral Presentation| APICURON: Crediting scientific contributions beyond publications |
| 10:15 | Matteo Andriolo |Oral Presentation| ArchetypalC: A High-Performance C++ Implementation of Archetypal Analysis for Large-Scale Bioinformatics with Interactive Visualization |
| 10:30 - 11:30 | Coffee break & Poster session |
Cancer bioinformatics chair(s) to be defined |
|
| 11:30 - 12:00 | Francesca Ciccarelli Barts Cancer Institute & The Francis Crick Institute invited speaker Determinants of response to immunotherapy in colon cancer: why space matters |
| 12:00 | Paolo Bresolin |Oral Presentation| General-Purpose Topology-Aware Embedding of Tumor Phylogenetic Trees with Graph Neural Networks |
| 12:15 | Emanuela Scafuri |Oral Presentation| Assessing Omics Layer Contributions in Unsupervised Multi-Omics Integration for Patient Stratification |
| 12:30 - 14:00 | Lunch and group photo |
| 14:00 | Michele Marziliano |Oral Presentation| A Spatial Multiplex Proteomics Approach to Study Tumor Microenvironment Remodeling in Treated Non-Small Cell Lung Cancer |
| 14:15 | Lorenzo Amir Nemati Fard |Oral Presentation| Communication Breakdown and Evolution of the Cancer Cell |
| 14:30 | Roberto Pagliarini |Oral Presentation| A computational analysis to decipher different transcriptomic signatures regulating gliomas heterogeneity |
| 14:45 | Elia Giuseppe Ceroni |Oral Presentation| MRI-based intratumoral heterogeneity mapping in Glioblastoma via self-supervised 3D Masked Autoencoder |
Omics data, methods and applications chair(s) to be defined |
|
| 15:00 - 15:30 | Ivan G. Costa RWTH Aachen University invited speaker From Cells to Samples: Algorithms for Multi-Scale Analysis of Spatial Disease Atlases |
| 15:30 - 16:30 | Coffee break & Poster session |
| 16:30 - 17:00 | Silvio Bicciato University of Padua invited speaker Computational analysis of single-cell spatial omics data: challenges and opportunities |
| 17:00 | Matteo Marchionni |Oral Presentation| Enhanced cell phenotyping in single-cell and spatial omics using the scPleiades pipeline |
| 17:15 | Giorgia Bucciarelli |Oral Presentation| RNAEventProfiler: A Statistical Framework for Detecting Direct RNA Modification Changes in Complex Experimental Designs |
| 17:30 | Veronica Guerrini |Oral Presentation| A Burrows-Wheeler Transform Index for Pangenomes |
| 17:45 | Sandro Gepiro Contaldo |Oral Presentation| A Bioinformatics Workflow for the Detection of Antimicrobial Resistance-Associated Genomic Variants |
| 18:00 | Alessandra Luciani |Oral Presentation| Characterization of Brain Microbiome in Neurodegenerative Disease via Metatranscriptomics |
| 18:15 | Eva KöNig |Oral Presentation| A scalable framework for multi-ancestry meta-analyses of complex traits across heterogeneous cohorts: a phosphate and calcium use case |
| 20:00 | Social dinner |
| Friday, 29 May | |
AI, Models and Tools chair(s) to be defined |
|
| 09:00 - 09:45 | Christine Orengo University College London keynote CATH and TED reveal novel insights into protein evolution and protein design |
| 09:45 | Cristian Taccioli |Oral Presentation| LLMsFold: Integrating Large Language Models and Biophysical Simulations for De Novo Drug Design |
| 10:00 | Giovanni Birolo |Oral Presentation| SurvCraft: Decomposing and Recombining Deep Survival Models for Fair Comparison |
| 10:15 | Luca Alessandri |Oral Presentation| REBEL (Reproducible Environment Builder for Explicit Library Resolution) |
| 10:30 - 11:00 | Coffee break |
Systems Biology and Multi-Omics chair(s) to be defined |
|
| 11:00 - 11:45 | Filippo Utro IBM T.J. Watson Research Center BITS Lecture From Classical to Quantum: New Computational Paradigms for Life Sciences |
| 11:45 | Livia Perfetto |Oral Presentation| Novel strategies to derive personalised mechanistic models and signalling-based biomarkers |
| 12:00 | Gioele Lazzari |Oral Presentation| A paradigm shift in genome-scale metabolic models reconstruction: introducing GRAP |
| 12:15 | Tania Alonso-VáSquez |Oral Presentation| Stochasticity in multi-layered Quorum Sensing systems |
| 12:30 - 14:00 | Lunch |
Proteins chair(s) to be defined |
|
| 14:00 - 14:30 | Gábor Erdős Eötvös Loránd University invited speaker Zero-Shot Prediction of Thermodynamic Properties of Proteins |
| 14:30 | Sergio Vulterini |Oral Presentation| Computational studies of the dynamics of the human iron exporter Ferroportin. Insight into the effect of pathogenic mutations in the transport mechanism. |
| 14:45 | Carlo Ferrari |Oral Presentation| Comparing Sequence and Graph Frameworks for Antibody Interaction Site Prediction |
| 15:00 - 15:10 | Biohackathon results |
| 15:10 - 15:20 | Announcements BITS2027 & BITS2028 |
| 15:20 - 15:30 | Final remarks |
| 15:30 - 15:45 | Break |
YOUNG BITS, RSG-Italy & CINI Young InfoLife Symposium chair(s) to be defined |
|
| 15:45 | Virginia Quadrotta |Oral Presentation| Asymmetric conformational dynamics of the mitochondrial choline carrier SLC25A48 revealed by molecular dynamics simulations |
| 16:00 | Gaia Faggin |Oral Presentation| The Cell Marker Accordion 2.0: An Entropy-Driven Framework for Interpretable Cell Type Annotation, Clustering, and Spatial Deconvolution |
| 16:15 | Omar Almolla |Oral Presentation| Topological Data Analysis reveals the fine structure of smooth muscle cell phenotypic modulation in human atherosclerotic plaques |
| 16:45 - 17:00 | Final remarks |
For any query regarding the BITS2026 congress, please write to: congress AT bioinformatics.it
