The cell is the basic unit of life, but only very recent technological advancements that span from single cell RNA-sequencing to live imaging, allowed scientists to actually observe and measure the behaviour of biological processes at the level of individual cell. These new technologies revealed that no two cells are exactly the same and subtle changes that make each one unique are emerging.
The increase in resolution is shaking our perspective on very basic biological processes and is revealing new cellular phenomena. This scientific revolution can pave the way for a novel interpretation of biological processes, especially those at the basis of complex phenotypes.
This free workshop focuses on the opportunities and challenges that the "single-cell revolution" brings at the biotechnological and data-analysis level, but also on the identification of new problems and paradigms in modern biology. Condensed in one day, we will see examples of the biological insights that can be gained while moving from “many “to “one”.
Topics: Single Cell Sequencing, Immunology, Epigenetics, Evolution, Bioinformatics
Organizers: Matteo Cereda, Matteo Osella, Valentina Proserpio, Michele Caselle
The workshop is free, for any question send an email to one of the following addresses:
- matteo.cereda@iigm.it
- mosella@to.infn.it
- caselle@to.infn.it
CONFIRMED SPEAKERS
- Dr Luigia Pace, Immune Regulation Lab, Italian Institute of Genomic Medicine (IIGM), Torino, IT
- Dr Davide Cittaro, Center for Translational Genomics and Bioinformatics, San Raffaele Hospital, Milan, IT
- Dr Davide Cacchiarelli, Genomic Medicine, Telethon Institute of Genomics and Medicine, Naples, IT
- Dr Giacomo Donati, Stem Cell Biology and Cell Plasticity Laboratory, University of Torino, Torino, IT
- Dr Valentina Proserpio, Epigenetics Lab, Italian Institute of Genomic Medicine (IIGM), Torino, IT
- Dr Valeria Ranzani, Integrative Biology, INGM-National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi", Milan, IT
- Dr Saveria Mazzara, Integrative Biology, INGM-National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi", Milan, IT
- Luca Alessandrì, Dept. of Molecular Biotechnology and Health Sciences, University of Torino, Torino, IT
- Dr Marco Antoniotti, Department of Informatics, Systems and Communication (DISCO), University of Milan Bicocca, Milan, IT
- Dr Natalia Kunowska, Immune Genomics, Cellular Genetics Programme, The Wellcome Trust Sanger Institute, Hinxton, UK
ORAL COMMUNICATION & POSTER SUBMISSION
DATE & VENUE
When: June 26th from 9:00 to 19:00
Where: Aula Darwin @ Molecular Biotechnology Center, Via Nizza 52, 10126 Torino, IT
PROGRAM
9:00 | 9:20 | Registration | ||
First Session | ||||
9:30 | 10:20 | Davide Cittaro, Translational Genomics and Bioinformatics, San Raffaele Hospital | ||
Analysis of single cell data: do's and don’ts | ||||
10:30 | 11:00 | Valentina Proserpio, Epigenetics Laboratory, Italian Institute for Genomic Medicine (IIGM) | ||
T.B.A. | ||||
11:00 | 11:30 | Coffee break | ||
11:40 | 12:20 | Davide Cacchiarelli, Genomic Medicine, Telethon Institute of Genomics and Medicine | ||
Dissecting cell fate decisions through single-cell transcriptomics | ||||
12:30 | 13:00 | Marco Antoniotti, Department of Informatics, Systems and Communication (DISCO), University of Milan Bicocca Milan, IT | ||
Reconstructing Mutational Graphs of Tumor Evolution from Single Cells Data | ||||
13:00 | 13:50 | Lunch break | ||
Second Session | ||||
14:00 | 14:50 | Luigia Pace, Immune Regulation Laboratory, Italian Institute for Genomic Medicine (IIGM) | ||
Linking heterochromatin architecture and CD8+ T cell fate commitment | ||||
15:00 | 15:30 | Valeria Ranzani, INGM-National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi" Milan, IT | ||
Single Cell Transcriptome Analysis of Human Tumor-Infiltrating CD4+ T cells | ||||
15:40 | 16:20 | Natalia Kunowska, Immune Genomics, Cellular Genetics Programme, The Wellcome Trust Sanger Institute, Hinxton, UK | ||
Evolutionary architecture of innate immune response | ||||
16:20 | 16:50 | Coffee break | ||
16:50 | 17:20 | Saveria Mazzara, INGM-National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi" Milan, IT | ||
Bioinformatic workflow assessment of different single-cell RNAseq platforms | ||||
17:30 | 18:00 | Luca Alessandrì, Dept. of Molecular Biotechnology and Health Sciences, University of Torino | ||
CASC: Classification Analysis of Single Cell Sequencing Data | ||||
18:00 | 18:30 | Giacomo Donati, Stem Cell Biology and Cell Plasticity Laboratory, University of Torino | ||
Understanding Wnt-mediated crosstalk between epidermal stem cells | ||||
18:30 | TBD | Social Drinks |
CONTACTS
For any further information drop an email to any of these addressess:
- matteo.cereda@iigm.it
- mosella@to.infn.it
- caselle@to.infn.it