Applicazioni bioinformatiche per l'analisi di dati di Next generation Sequencing
SCOPE AND TOPICS

Next Generation Sequencing (NGS) methods are revolutionizing genomic and functional-genomics research. However, the manipulation and interpretation of the huge amounts of data produced present significant computational challenges.

To provide an overview of current ultra-high throughput sequencing platforms and introduce NGS data analysis strategies for genomic sequencing, transcriptome analysis ChIP-Seq and other applications, we have organized a workshop with practical sessions.

Topics will include:

Next Generation Sequencing platforms (Roche 454, Illumina Solexa, ABI SOLiD)
Strategies for mapping NGS reads to reference sequences
Genome re-sequencing and assembly, SNP discovery
Clustering of reads from expressed sequences (peak finding)
Integration of gene expression data and genome annotation
Estimation of gene expression levels and profiles
Analysis of splicing and alternative splicing
Small RNA discovery and characterization
Analysis of genome methylation
Chip-seq data analysis
The workshop will include seminars to illustrate the theoretical basis of the computational approaches and analysis workflows based on real examples.

Practical sessions will follow, where the participants will use state-of-the art tools for real data analysis.

Workshop Scientific and Organizing Committee

Graziano Pesole, University of Bari and ITB-CNR, Bari (Workshop Chair)
Ernesto Picardi, University of Bari
Elisabetta Sbisà, ITB-CNR, Bari
Sabino Liuni, ITB-CNR, Bari
Apollonia Tullo, ITB-CNR, Bari
Domenica D'Elia, ITB-CNR, Bari
Antonio Baldini, IGB-CNR, Naples
Tiziana Castrignanò, CASPUR, Rome
David Horner, University of Milan
Giulio Pavesi, University of Milan
Flavio Mignone, University of Milan

Workshop Secretary and Organization

Angela Evangelista, University of Bari

The number of participants is limited to 80 for the lectures and to 30 for the practical sessions. The registration form is available here.

For information please contact a [dot] evangelista [at] biologia [dot] uniba [dot] it

Workshop Venue

Aula 1 - Facoltà di Scienze Biotecnologiche, Labobiotech, University of Bari
via Fanelli, 204

The practicals will be located at:
Aula Shannon - Dipartimento di Informatica, University of Bari
via Orabona, 4