Cancer is a complex disease involving several intertwined phenomena and events, which collude to unleash the tumor cells inherent programs to proliferate, live, and move; thus, it is the malfunction of the biomolecular machinery responsible for the "checks and balances",normally governed by various complex feedback loops among a population of various cell types. Breakdown of this machinery leads to uncontrolled growth of a cell population being selected by evolutionary pressure that ultimately costs the very survival of the host.
Understanding the many intricacies of all these interactions at the subcellular, cellular and tissue levels has greatly benefitted from the ever-improving applications of algorithmic, statistical and mathematical modeling tools. Moreover, during the past 15 years, new measurement technology for gene expression and, more recently, "deep"genome sequence data, have produced vast amount of data, waiting tobe analyzed to deliver new interpretations. The design of novel "wet" experiments and appropriately matched algorithmic, statistical and mathematical modeling tools are expected to become the key to successful oncological science and practice.
The Workshop and School on Cancer Development and Complexity seeks to convene researchers from various related disciplines to explore multiple facets of the challenges posed by cancer a "disease of the systems." The workshop will provide opportunities for the researchers to exchange new ideas and viewpoints, forge new collaborations and train the next generation of young scientists.
Participants are encouraged to present their work in two sessions and poster presentations that will be held during the workshop.
The program will provide an introduction to both cancer biology and mathematical and statistical methods used in analyzing the datasets currently being produced by several laboratories around the world.Next the program will provide an opportunity to interact with world renowned cancer and bioinformatics researchers and the chance for attendees to present their current work. Finally, all the attendees will receive a certificate of completion of the School.
*** School Directors
* Marco Antoniotti, BIMIB, Dipartimento di Informatica, Sistemistica e Comunicazione, Universita` degli Studi di Milano Bicocca, Milan, Italy.
* Bud Mishra, Courant Institute of Mathematical Sciences, and Tandon School of Engineering, NYU, New York, NY, USA.
*** Confirmed Speakers
* Charles Cantor, Agena Biosciences, Sequenom, Retrotope and Boston University, USA
* Philippe Gorry, GREThA, Universite` de Bordeaux, France
* Marcin Imielinsky, Weill Cornell Medical College, Cornell University, New York, USA.
* Bud Mishra, Courant Institute of Mathematical Sciences and Tandon School of Engineering, NYU, New York, USA.
* Eugenio Montini, San Raffaele Telethon Institute for Gene Therapy, HSR-TIGET, Milan, Italy
* Quaid Morris, Banting and Best Department of Medical Research Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Canada.
* Ben Raphael, Princeton University, Princeton, USA.
* Andrea Sottoriva, The Institute of Cancer Research, London, UK.
* Simon Tavare', Cancer Research UK Cambridge Institute, Cambridge, UK.
*** Local Organization
* Alex Graudenzi (BIMIB)
* Giancarlo Mauri (BIMIB)
* Luca De Sano (BIMIB)
* Nadia Tansini (Fondazione Alessandro Volta)
* BIMIB, Dipartimento di Informatica, Sistemistica e Comunicazione, Universita` degli Studi di Milano Bicocca, Milan, Italy (http://bimib.disco.unimib.it)
* Fondazione "Alessandro Volta", Como, Italy (http://fondazionealessandrovolta.it)
* Lake Como School of Advanced Studies, Como, Italy (http://lakecomoschool.org)
Villa del Grumello (http://www.villadelgrumello.it)
Registration fees include participation to the school, social events,coffee breaks and school material.
Early registration (until March 15th, 2017): 350.00 EUR (*)
Regular registration (after March 15th, 2017): 400.00 EURDaily, on site registration: 100 EUR (social dinner extra)
(*) Participants affiliated with the four Universities supporting theLake Como Schools (Milano Statale, Pavia, Milano Bicocca and Insubria)qualify for a 320.00 EUR early registration fee. All fees include VAT.
The first registrants may ask to be hosted directly at Villa DelGrumello (in a shared accommodation) for an additional cost of 37.00EUR, VAT included, per night up to capacity (10 places).A list of local hotels will be provided.