Aim and scope: The theme of the school, RNAs : structure, function and therapy, falls within the areas of Bioinformatics & Biomedicine, and deals specifically with bioinformatics and biomedical aspects of RNAs analysis. There are four lecture series, each of three hours, a lecture series of one hour, and nine tutorials, each of one hour. The lectures will cover fundamental aspects relating to the study and the analysis of transcription and translation mechanisms and their spatial-temporal regulation. Gene regulatory factors that control the expression of genomic information come in a variety of flavors, with transcription factors and microRNAs representing the most numerous gene regulatory factors in multicellular genomes. Two series of lectures are devoted to RNA interference, with special emphasis on mechanisms of post transcriptional regulation by microRNAs in vivo with case studies from the brain and the involvement of microRNAs in cancer, while the other two are devoted to mathematical, physical and computational methods needed to analyse RNAs. The tutorials will cover the most recent advances in computational methods for RNAs: sequences and structures. Moreover, they will also highlight recent additional results on protein-RNA interactions. Thus they nicely complement the main lectures. As it is clear from the enclosed bibliography, the selected themes have received much attention in the scholarly literature that ranges from Nature to BMC Bioinformatics and Bioinformatics. In its entirely the planned summer school will allow young researchers interested in bioinformatics and biomedicine to be exposed to cutting edge results in the increasingly important area of RNAs analysis in biology.