Program
27 June 
09:00 - 13:00 Workshop BITS2018-CAREER MORNING
13:00 Registration and poster hang-up
14:30 Opening remarks - Prof Federico Bussolino, vice-dean for research of University of Turin
- Dr Paola Pisano, Council member for innovation and smart city for the city of Turin and Assistant professor at Computer Science department
- Prof Luca Console, Computer Science Department Director
Molecular Evolution analysis
chairs Gustincich, Calogero
14:45 - 15:30 Stefano Gustincich Preparata Lecture - Invited Speaker Junk DNA in health and disease
15:30 Matteo Fumagalli Deep learning algorithms in evolutionary genomics: detecting signatures of natural selection
15:45 Massimiliano Volpe Evidences of somatic retrotransposition in the octopus brain
16:00 Serena Aneli Ancient genomic signatures in the Italian population
16:15 Davide Marnetto Haplostrips: revealing population structure through haplotype visualization
16:30 - 17:00 Coffee Break - Poster Session
17:00 - 20:00 BITS members meeting
28 June 
Gene regulation, transcriptomics and epigenomics
chairs Ferrari, Mazza
09:00 - 09:45 BITS Lecture
09:45 Claudio Lo Giudice Detecting A-to-I RNA editing signatures in long RNA-Seq reads.
10:00 Carmen Maria Livi A comprehensive framework for ChIP-seq data quality assessment
10:15 Elisa Mariella A functional strategy to characterize expression Quantitative Trait Loci
10:30 Paolo Kunderfranco Stress The System: single-cell RNA sequencing on a panel of 9 different cell types from in-vivo, in-vitro, and clinical samples
10:45 Andreas Zanzoni Perturbed human sub-networks by Fusobacterium nucleatum candidate virulence proteins
11:00 - 11:30 Coffee Break - Poster Session
Algorithms in bioinformatics
chairs Pesole, Armano
11:30 Antonio Colaprico Moonlight: a tool for biological interpretation and driver genes discovery
11:45 Simone Spolaor GenHap: Haplotype Assembly Using Genetic Algorithms
12:00 Dario Righelli Differential Enriched Scan 2 (DEScan2): a fast pipeline for broad peak analysis
12:15 Giacomo Baruzzo SPARSim: taking account of data sparsity in single cell and 16S rRNA gene sequencing
12:30 Matteo Comin Better quality score compression through sequence-based quality smoothing
12:45 Luisa Pugliese SAFAN-ISP: small molecule in-silico profiling with experimental reliability
13:00 - 14:00 Lunch - Poster Session
Bioinformatic challenge in microbiome research
chairs Segata, Cordero
14:00 - 14:45 Nicola Segata Invited Speaker Computational metagenomics for large-scale strain-resolved human microbiome studies
14:45 Fabio Marroni Do you cov me? Effect of coverage rarefaction on species identification in complex matrices
15:00 Alessandro Silvestri SmallRNAome characterization of a plant-fungal root symbiosis
15:15 Paolo Manghi Combined metagenomic analysis of colorectal cancer datasets defines cross-cohort microbial diagnostic signatures
15:30 Giulio Ferrero Gut microbiome composition and small RNA spectra in human stool for colorectal cancer detection
15:45 Jia Qian Metagenomic Contigs Binning with Probabilistic k-mers Statistics
16:00 Francesco Asnicar An integrated pipeline for large-scale phylogenetic characterization of genomes and metagenomes
17:00 - 19:00 Social Activities
20:00 Social Dinner
29 June 
Systems Biology and Biological Networks
chairs Zavolan, Caselle
09:00 - 09:45 Mihaela Zavolan Invited Speaker Regulation of translation in relation to cell fate
09:45 Gaia Ceddia Using Non-Negative Matrix Tri-Factorization to find candidate drugs for the treatment of Alternating Hemiplegia of Childhood (AHC)
10:00 Paolo Martini Gaining power from multi-omic data integration and pathway topology: improvement of prognostic gene module identification
10:15 Simone Pernice Connector: A computational approach to study intratumor heterogeneity.
10:30 Lisanna Paladin Resources for repeat protein structure annotation: RepeatsDB and RepeatsDB-lite
10:45 Louis Faure Gene Network Inference from pseudotime ordered scRNAseq data
11:00 - 11:30 Coffee Break - Poster Session
Proteomics
chairs Romano, Orro
11:30 Guidantonio Malagoli Tagliazucchi A computational framework for the identification of genes modules epigenetic regulated and targetable by drugs at the level of single patient.
11:45 Serena Dotolo Detection of the impairment of allosteric communication in Sirtuin2 proteins through molecular dynamics and residue coevolution
12:00 Romina Oliva Dissecting the structural determinants of a class of anti-TG2 antibodies by an integrated computational and experimental approach
12:15 - 13:00 Theodore C. Goldstein invited speaker Cancer Bioinformatics: This way to the revolution
13:00 - 14:00 Lunch - Poster Session
14:00 - 18:00 Workshop BITS2018-PRECISION ONCOLOGY
EuroClone S.p.A. Personal Genomics BioPmed | Piemonte Innovation Cluster Cellular and Molecular Biology - Università degli Studi di Torino Dottorato in Sistemi Complessi per le Scienze della Vita - Università degli Studi di Torino Dipartimento di Informatica dell'Università degli Studi di Torino Università di Torino