Wednesday, 12 June
08:30 - 09:00	Registration & sign-in
Cosmic codes: Bridging Space Explorations and Bioinformatics chair(s) Gabriella Viero
09:00 - 09:05	Workshop opening
09:05 - 09:30	Lorenzo Bruzzone Space Science and Technology: from Planetary Exploration to Earth Observation
09:30 - 10:00	Roberto Battiston Space Exploration, status and perspectives
10:00 - 10:30	Coffee Break Trento Expo
10:30 - 11:15	Marta Murgia Signatures of muscle disuse in spaceflight and bed rest revealed by single muscle fiber proteomics
11:15 - 11:45	Emiliano Biasini The ZePrion Experiment: Crystallizing Protein Folding Intermediates on the International Space Station
11:45 - 12:15	Silvia Holler Geologically empowered origin of life
12:15 - 13:45	Lunch & Poster preparation Trento Expo
13:45 - 14:00	Opening remarks
Bioinformatics AI, Models and Tools (part 1) chair(s) Enrico Blanzieri
14:00 - 14:30	Nicola Segata University of Trento, IEO PREPARATA LECTURE Computational metagenomics to model natural and therapeutic human microbiome transmission
14:30 - 15:00	Giuseppe Jurman Fondazione Bruno Kessler INVITED Generative AI in sequencing: enhancing models by synthetic omics data
15:00	Sofia Mongardi |Oral Presentation| Integrating biological networks for bulk RNA-seq profile generation
15:15	Anna Marabotti |Oral Presentation| Development of an automated pipeline to predict protein structures.
15:30	Matteo Manfredi |Oral Presentation| Alpha&ESMhFolds: a web server for the comparison of 42,942 AlphaFold2 and ESMFold models of the human reference proteome
15:45	Silvia Galfrè |Flash Talk| From Gene to Cluster: COTAN v2 for Improved scRNA-seq Analysis and Unsupervised Clustering
15:52	Giovanni Micale |Flash Talk| PACO: a Shiny app for comparing perturbed pathways associated with different phenotypes
16:00 - 16:30	Coffee Break Trento Expo
16:30 - 17:10	Twenty years of BITS Raffaele Calogero, Manuela Helmer-Citterich, Luciano Milanesi, Graziano Pesole, Giorgio Valle BITS LECTURE
17:10 - 19:00	BITS members meeting
19:00 - 21:00	Welcome cocktail Augustinian Cloister
Thursday, 13 June
08:30 - 09:00	Registration & sign-in
Bioinformatics Core Facilities and Research Infrastructures chair(s) Matteo Pallocca & Arnaud Ceol
09:00 - 09:30	Alessandro Cestaro CNR-IBIOM ELIXIR INVITED ELIXIRxNextGenIT, consolidating the ELIXIR Italian Node
09:30	Alberto Riva |Oral Presentation| The National Facility for Data Handling and Analysis at Human Technopole
09:45	Alexander Miguel Monzon |Oral Presentation| DRMAAtic: dramatically improve your cluster potential
10:00	Sandro Gepiro Contaldo |Oral Presentation| Driving Microbial Research Forward: Scalable Bioinformatics Workflows as a Service in the Italian Microbial Resource Research Infrastructure
10:15	Claudio Lo Giudice |Oral Presentation| Development of a state of the art computational environment for handling human genetic data: the effort of ELIXIR-IT
10:30 - 11:00	Coffee Break Trento Expo
Systems Biology chair(s) Luca Marchetti
11:00 - 11:30	Silvia Parolo COSBI INVITED Exploring New Therapeutic Opportunities for Common and Rare Disorders through Network-Based Drug Repurposing
11:30	Veronica Venafra |Oral Presentation| SignalingProfiler bridges multi-omics data with phenotypic hallmarks and empowers drug repurposing
11:45	Simone Pernice |Oral Presentation| Synthetic tumors: a data-driven approach to simulate the evolution of mutational profiles and clonality in cancer
12:00	Guido Zampieri |Oral Presentation| Integrated metagenome- and metatranscriptome-scale metabolic modelling for uncultured microbial systems
12:15	Tania Alonso-VáSquez |Flash Talk| An ecological perspective on persisters resuscitation
12:30 - 14:30	Lunch & Poster Session 1 Trento Expo
Multi-Omics chair(s) Livia Perfetto & Ettore Mosca
14:30 - 15:00	Marco Moretto Fondazione Edmund Mach INVITED The Grapedia Initiative: Building the Grapevine Genomic Encyclopedia
15:00	Chiara Damiani |Oral Presentation| Leveraging high-throughput data to characterize cancer metabolic heterogeneity
15:15	Chiara Carrino |Oral Presentation| Integrating transcriptomic and phosphoproteomic data to discover dysregulated transcriptional networks in lung cancer
15:30	Luisa Bisceglia |Oral Presentation| Unveiling Drug sensitivity and GPCR Expression Patterns: A Gateway to Targeted Cancer Therapy
15:45	Marco Fantuz |Flash Talk| SINGLE-NUCLEI MULTIOMIC APPROACH REVEALS PERMANENT REPROGRAMMING OF EXOCRINE CELLS AFTER PANCREATITIS
15:52	Ettore Aiello |Flash Talk| A multi-species multi-omics database to a gain insight into CDKL5 Deficiency Disorder
16:00 - 16:30	Coffee Break Trento Expo
16:30	Alice Chiodi |Oral Presentation| Explaining the molecular basis of a complex process through multi-omics data integration and machine learning: an application to microbiota-gut-brain axis in autism spectrum disorder.
Proteins chair(s) Angelo Facchiano
16:45 - 17:15	Johannes Rainer Eurac, Bolzan INVITED An Open Software Development-based Infrastructure for Efficient Mass Spectrometry Data Analysis
17:15	Nancy D'Arminio |Oral Presentation| Deciphering Beta Turn Diversity: Unveiling the Role of Carbonyl-Carbonyl Interactions
17:30	Maria Milanesi |Flash Talk| Transient interactions between the fuzzy coat and the cross- β core of brain-derived Aβ42 filaments
17:40 - 17:55	Presentation of BITS 2025
19:30 - 23:30	Social Dinner Villa Bortolazzi
Friday, 14 June
08:30 - 09:00	Registration & sign-in
Bioinformatics AI, Models and Tools (part 2) chair(s) Raffaele Calogero
09:00 - 09:30	Giovanni Iacca University of Trento INVITED When Explainable AI and Evolutionary Computation meet
09:30	Edoardo Bizzotto |Oral Presentation| FEEDS and CICERON: a computational pipeline for prediction and functional classification of biopeptides
09:45	Davide Rigoni |Oral Presentation| TumFlow: An AI Model for Predicting New Anticancer Molecules
10:00	Eva Viesi |Oral Presentation| Predicting Novel Molecular Interactions through Compound Signatures and Target Descriptors
10:15	Grete Francesca Privitera |Flash Talk| BacExplorer - Bacteria Functional Annotation and Mutation Analysis Pipeline
10:22	Vincenzo Bonnici |Flash Talk| Fragment length distribution fingerprints for microbial activity prediction via unbalanced machine-learning models
10:30 - 11:00	Coffee Break Trento Expo
11:00	Silvia Cascianelli |Oral Presentation| Machine learning for expression-based multi-label patient subtyping and advanced recognition of primary and secondary assignments
11:15	Dramane Dagnogo |Flash Talk| Machine Learning applied to association studies on small and unbalanced sample data
11:22	Alessia Canevotti |Flash Talk| miR-RF: a machine learning based tool for the in-silico pre-miRNAs annotation/classification
High Resolution RNA Computational Biology chair(s) Erik Dassi
11:30 - 12:00	Eva Maria Novoa CRG Barcelona INVITED Decoding the mRNA and tRNA epitranscriptome at single molecule resolution
12:00	Christian Ramirez |Oral Presentation| METTL3 inhibition modulates RNA structure, A-to-I editing and immune response in leukemia models
12:15	Chakit Arora |Oral Presentation| GPCR Signaling Axes in Cancer: Insights from Omics Analysis Reveal New Opportunities for Precision Medicine
12:30 - 14:30	Lunch & Poster Session 2 Trento Expo
14:30 - 15:00	Levi Waldron CUNY University, New York INVITED Databases and methods for efficient learning from published data in cancer genomics
15:00	Gaia Tussardi |Flash Talk| Interactive exploration of cell-cell communication results from single-cell RNA sequencing data through a webapp
Data management, sharing and FAIRness chair(s) Flavio Licciulli
15:07 - 15:37	Simon Hodson CODATA INVITED FAIR to Enable Cross-Domain Research
15:37	Eliseo Martelli |Flash Talk| CREDO: Customizable, Reproducible, Dockerfile Generator for Bioinformatics Applications
16:00 - 16:15	Closing Remarks. Poster & Talk awards
YOUNG BITS, RSG-Italy & CINI Young InfoLife Symposium chair(s) Emma Busarello & Gaia Tussardi
16:15 - 16:27	Presentation of YOUNG BITS, RSG-Italy, CINI Young-InfoLife groups Claudia Mengoni, Simone Pernice
16:27	Martina Coffa |Oral Presentation| MATITE - a Multi-omic Approach To Investigate The human repeatomE
16:40	Sachithra Kalhari Yaddehige |Oral Presentation| GBRAP: A Comprehensive Tool and a Database to Measure Genomic Characteristics
16:53	Riccardo Aucello |Oral Presentation| A comprehensive analysis of metagenomic data in subjects with Multiple Sclerosis
17:06	Sara Baldinelli |Oral Presentation| Validation of a non-invasive low-volume transcriptomic analysis to predict cervical cancer progression in HPV positive patients
17:19	Alessandro Ricci |Oral Presentation| ASO design for the disruption of the NSP1 - 5’UTR interaction of SARS-CoV 2
17:32	Piero Mariotto |Oral Presentation| Limitations of the co-occurrence-based approach in the inference of microbiota interaction networks.
17:45 - 19:00	CINI InfoLife Meeting
19:00 - 21:00	AperiBITS Trento Expo
Saturday, 15 June
09:30 - 12:30	David Tacconi & Francesco Guzzonato (School of Innovation) Workshop "Bioinformatics, Innovation & Entrepreneurship" School of Innovation
15:50 - 18:30	Dragonboat on the Caldonazzo lake (meeting point in front of the Trento train station, at 13.50) Centro Nautico Universitario AugsburgerHof