Laura Bonati
Socio Ordinario
Professore associato
Università degli Studi di Milano-Bicocca
Contact Information
RESEARCH AREA
algorithms
RESEARCH ACTIVITY
1. Studio di strutture proteiche mediante metodi bioinformatici e di modellistica molecolare.
2. Modellistica molecolare delle interazioni legante-proteina e proteina-proteina.
3. Modellistica molecolare dei meccanismi di azione biologica di contaminati ambientali.
2. Modellistica molecolare delle interazioni legante-proteina e proteina-proteina.
3. Modellistica molecolare dei meccanismi di azione biologica di contaminati ambientali.
SELECTED PUBLICATIONS
1.A. Pandini, L. Bonati, “Conservation and Specialisation in PAS domain dynamics” Protein Eng. Des. Sel. (2005) 18:127-137.
2. Pandini A., Denison M.S., Song Y., Soshilov A.A., Bonati L. (2007). Structural and functional characterization of the Aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis. Biochemistry, 46, 696-708.
3. Pandini A., Bonati L., Fraternali F., Kleinjung J. (2007). MinSet: a general approach to derive maximally representative database subsets by using fragment dictionaries and its application to the SCOP database. Bioinformatics, 23, 515-516.
4.Pandini A., Mauri G., Bordogna A., Bonati L. (2007). Detecting similarities among distant homologous proteins by comparison of domain flexibilities. Protein Engineering Design and Selection, 20, 285-299.
5. Pandini A., Soshilov A.A., Song Y., Zhao J., Bonati L., Denison M.S. (2009). Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis. Biochemistry, 48, 5972-5983.
2. Pandini A., Denison M.S., Song Y., Soshilov A.A., Bonati L. (2007). Structural and functional characterization of the Aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis. Biochemistry, 46, 696-708.
3. Pandini A., Bonati L., Fraternali F., Kleinjung J. (2007). MinSet: a general approach to derive maximally representative database subsets by using fragment dictionaries and its application to the SCOP database. Bioinformatics, 23, 515-516.
4.Pandini A., Mauri G., Bordogna A., Bonati L. (2007). Detecting similarities among distant homologous proteins by comparison of domain flexibilities. Protein Engineering Design and Selection, 20, 285-299.
5. Pandini A., Soshilov A.A., Song Y., Zhao J., Bonati L., Denison M.S. (2009). Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis. Biochemistry, 48, 5972-5983.
OTHER MEMBERSHIPS
ISCB, BITS
MAIN TEACHINGS
Chimica Fisica, Chimica Fisica Superiore, Modellistica Molecolare.
